Preventive radiation to the other breast after breast cancer surgery
Part of Cancer, Skin clinical trials.
This study looks at whether “preventive” radiation to your other (opposite) breast can lower the chance of future breast cancer in people at higher genetic risk. You must have had surgery for early-stage breast cancer and agree to avoid removing the other breast and ovaries.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are female and between 30 and 70 years old
- You have early-stage breast cancer (stage 0 to III), treated with lumpectomy or mastectomy within the past year
- You have had sentinel or axillary lymph node surgery (sentinel or ALND) and your lymph node results are known
- You carry a harmful (deleterious) gene change in BRCA1, BRCA2, or PALB2
- You can safely receive radiation (no major radiation-blocking health problems) and you can get a breast MRI
- You do NOT have metastatic breast cancer, and you have not had prior radiation to the breast/chest wall for non-treatment reasons
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial looks at whether adding targeted radiation to lymph nodes after breast surgery can lower the chance of breast cancer coming back in people with higher-risk, node-negative disease. If you qualify, you may get a planned radiation approach designed for prevention, not treatment of spread.
This trial tests giving a focused, higher dose of radiation to the lymph nodes above the collarbone after breast cancer treatment. It is for patients whose cancer did not fully disappear from those nodes after pre-surgery chemotherapy, to see if extra radiation can help prevent recurrence.
This trial is for women aged 55 or older with very early-stage breast cancer (stage 0 or 1) who want to save their breast. It tests giving a single dose of radiation during the lumpectomy instead of weeks of daily radiation afterward.
This Phase 3 study tests a specific plan that combines chemotherapy (and sometimes targeted medicines) with radiation before surgery for one breast. It may help shrink breast cancer and improve treatment timing, based on how well tumors respond.
This trial studies whether a specific radiation approach after lumpectomy can be helpful for certain people with early breast cancer that did not spread to lymph nodes at diagnosis. It focuses on people who finish neoadjuvant (before-surgery) treatment and reach a full response on final pathology.
This trial is testing whether giving radiation to nearby lymph nodes after surgery can help prevent breast cancer from coming back. It is for women with a specific type of breast cancer that has spread to a few lymph nodes but can be removed with surgery.
Hear when a new Breast cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.