Statin use after valve surgery to prevent heart rhythm trouble
Part of Heart & circulation clinical trials.
This study looks at whether taking statin medicines around the time of surgical aortic valve replacement can lower the chance of a common post-surgery heart rhythm problem called atrial fibrillation. It also compares statin-related factors in people who are at the time of surgery in normal rhythm and not on strong rhythm-stabilizing medicines.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are having planned (elective) single aortic valve replacement surgery with a tissue (bioprosthetic) valve
- Before surgery, your heart rhythm is normal (sinus rhythm) and you are not taking anti-arrhythmia drugs (except beta-blockers)
- You have taken a statin medicine (cholesterol-lowering “statins”) in the last 3 months, for at least 7 days
- You are older than 60 years
- You are able and willing to sign consent to be randomly assigned to a study group
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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