PEEP settings guided by lung pressure in pulmonary fibrosis
Part of Lungs & breathing clinical trials.
This trial tests whether using lung-pressure measurements to adjust ventilator PEEP (a breathing-support setting that keeps airways open) can help people with pulmonary fibrosis who are on a breathing machine for acute respiratory failure. It may improve breathing comfort and oxygenation by finding the best PEEP level for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have pulmonary fibrosis with a UIP pattern (a specific pattern seen on lung scans/biopsy).
- You are currently intubated (a tube in the windpipe) and on a ventilator for acute respiratory failure.
- Your breathing team plans to adjust PEEP (ventilator “positive end-expiratory pressure”) during this trial.
- You do not have chest wall deformities (a change in the shape of your chest).
- You do not have chronic obstructive pulmonary disease (COPD).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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