Study tonsil cell changes in children with sleep apnea
Part of Brain & nervous system, Ear, nose & throat clinical trials.
This study uses a lab method called single-cell sequencing to look at tiny cells from tonsil tissue in children. It compares children with obstructive sleep apnea to children without it, to better understand what’s happening in the throat and how it may relate to needing tonsil removal.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child is Chinese and age 6 to 11 years old
- Your child has habitual snoring (at least 3 nights per week) plus a sleep study result showing OSA (OAHI at least 1 per hour)
- Your child’s doctor recommends adenotonsillectomy (tonsil and adenoid removal) due to enlarged tonsils/adenoids
- Your child has not had prior surgery on the upper airway
- Your child does not have a genetic/syndrome condition, neuromuscular disorder, immune deficiency, metabolic syndrome, or craniofacial abnormalities
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two different exercises (called oral reeducation) to see which works better for children who still have breathing problems during sleep even after getting their tonsils or adenoids removed. It helps kids breathe easier at night.
This study tests a personalized surgical approach for children with moderate to severe obstructive sleep apnea who have small tonsils. The goal is to see if tailored surgery improves their breathing during sleep and overall health.
This study compares two types of tonsil surgery to see which works better for adults with obstructive sleep apnea caused by large tonsils. It may help you breathe better during sleep.
This trial is testing whether removing enlarged tonsils can help treat obstructive sleep apnea in adults. If you have sleep apnea and your tonsils are large, this surgery might improve your breathing and sleep.
This study looks at breathing problems that can happen after tonsil or adenoid surgery in children who have sleep apnea. Researchers want to learn more so they can make surgery safer for kids.
This study looks at whether removing tonsils and adenoids can help improve spine curves in children who have mild sleep-disordered breathing. It may help prevent scoliosis from getting worse.
Hear when a new Obstructive Sleep Apnea of Child trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.