Clin2
NCT05155137Possibly a fitRecruiting

Daily pill and home risk check to prevent stroke and memory loss

StrokeCognitive Decline

Treatments studied

Part of Brain & nervous system, Heart & circulation, Mental health clinical trials.

This Phase 3 trial tests whether a daily “polypill” plus a simple home risk-check plan can lower the chance of stroke and future thinking/memory problems. It is aimed at adults at moderate risk but who have not had stroke or heart disease before.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
8,518 people
Ages
50 years to 75 years
Study type
Interventional

Who can take part

  • You are between 50 and 75 years old
  • You have never had a stroke, a “mini-stroke” (TIA), or known heart and blood vessel disease
  • Your systolic blood pressure is between 121 and 139 (the top number on a blood pressure reading)
  • You have at least one lifestyle risk factor, such as smoking, being overweight, low activity, or a poor diet
  • You have access to a cell phone that can receive text messages
  • You are able to live at least 5 years and are not in another research study

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05963568Recruiting· Phase 3
Prevent more strokes with a daily anti-clotting heart pill

This Phase 3 trial tests whether a daily “polypill” can reduce the chance of another stroke after a recent ischemic stroke. It may help people by improving several heart-and-blood-vessel risks at once, but only if it fits safely with their medical situation.

Parakou
NCT07414732Recruiting
Testing a new approach to help stroke survivors take blood pressure pills

This trial tests a simple program to help people who have had a stroke stick with their blood pressure medication. It uses text messages and a medication organizer to make it easier to remember pills and keep blood pressure under control.

Boston, Massachusetts
NCT07092371Not yet recruiting
Smartphone program to reduce stroke risk

This study uses a smartphone app to share health tips and reminders that may help lower your risk of having a stroke. It aims to see if this kind of digital support can improve your brain health and overall well-being.

Hangzhou, Zhejiang
NCT06919835Not yet recruiting· Phase 3
Cilostazol to prevent another stroke in Africa

This study tests whether the drug cilostazol, when added to your usual aspirin or clopidogrel, can help prevent another stroke. It is being done in Africa and may be a good option if you've recently had a stroke or mini-stroke and want to lower your risk of another one.

Kumasi
NCT05030818Recruiting· Phase 4
Study of heart risk changes using a daily polypill

This trial looks at how a daily “polypill” affects coronary (heart blood vessel) risk factors in adults who already take this polypill for prevention after a prior heart event. If you’re eligible, you’ll complete several study visits so the team can compare risk factors over time.

Gijón, Principality of Asturias
NCT07679828Recruiting
Polypill for multiple heart and diabetes risk factors

This study tests a single daily pill combining several medicines to lower blood pressure and cholesterol in people with type 2 diabetes. Taking one pill may be easier than taking multiple medicines, which could help you stay healthy.

Zhengzhou, Henan

Hear when a new Stroke trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.