Clin2
NCT05238610Possibly a fitRecruiting

Registry for older adults with stroke of unclear cause and PFO

Embolic Stroke of Undetermined Source

Part of Genetic & congenital, Heart & circulation clinical trials.

This study follows adults over 60 who had a stroke where the cause is unclear, and where a heart opening (PFO) may have contributed. It mainly collects information to better understand this stroke pattern and how these patients do over time.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
1,200 people
Ages
60 years and older
Study type
Observational

Who can take part

  • You must be over 60 years old
  • Your stroke diagnosis must be within 180 days (about 6 months) of when symptoms started
  • Your heart test (TTE or TEE) must show a PFO linked to your stroke
  • Your stroke should be labeled ESUS, meaning no clear cause was found
  • You (or your legal representative) must agree to join

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07479147Recruiting
Stroke prevention in elderly by PFO closure vs blood thinners

This trial compares two treatments for preventing another stroke in older adults who have a PFO (a small hole in the heart). It tests whether closing the hole with a device works better than using blood-thinning medication.

Taichung
NCT06156670Recruiting
A study of closing a PFO to prevent strokes

This trial looks at the safety and results of closing a PFO (a small hole in the heart) in people who have had a stroke or embolism with no other clear cause. If you qualify, doctors will close your PFO using a small tube inserted through a blood vessel and then follow your health over time.

Moscow
NCT05537753Recruiting
PFO closure device test after recent unexplained stroke

This trial tests whether closing a hole in the heart (a PFO) with a special device can help prevent another stroke after an unexplained stroke. You may be a candidate if your stroke likely happened because blood can pass through this PFO.

Little Rock, Arkansas
NCT06983795Not yet recruiting
PFO and Stroke Study in Asia-Pacific

This study looks at a small hole in the heart called a PFO, which may be linked to strokes. It aims to better understand how the heart and brain interact, and may help guide future treatments for people with PFO who have had a stroke or mini-stroke.

Singapore
NCT04339699Recruiting
PFO closure comparison trial for cryptogenic stroke

This trial studies ways to close a patent foramen ovale (PFO) to help prevent another stroke in people whose prior stroke had an unknown cause. If you qualify, you may receive one of the PFO closure approaches the study is comparing.

Tucson, Arizona
NCT05907694Recruiting
Treatment of stroke from PFO, with or without closure

This study looks at whether treating a history of “cryptogenic” stroke (stroke with no clear cause) using a patent foramen ovale (PFO) closure, plus medical therapy, is better than medical therapy alone. It focuses on people over 60 with a heart shunt seen on an ultrasound of the heart.

Québec, Quebec

Hear when a new Embolic Stroke of Undetermined Source trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.