Clin2
NCT05268614Possibly a fitRecruiting

Risk-based reduced chemo and radiation for HPV throat cancer

Oropharyngeal Squamous Cell Carcinoma

Treatments studied

Part of Cancer clinical trials.

This trial tests whether using a lower intensity (reduced) chemo-radiation plan can work for some people with HPV-related oropharyngeal (throat) cancer without losing effectiveness. It may help reduce side effects while still controlling the cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
250 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 or older, with no upper age limit
  • Your cancer is HPV-related (HPV and/or p16 positive) and located in the oropharynx
  • Your scans show no spread to the lungs within about 12 weeks of starting treatment
  • You can take chemotherapy and your overall health is good enough (ECOG 0 to 2)
  • Your blood counts and organ function (kidney and liver) meet minimum levels before treatment
  • You have not had certain past treatments, like prior radiation to the head and neck

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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