Clin2
NCT05271240Possibly a fitRecruiting

Targeted brain-artery drug added to standard treatment for new GBM

GlioblastomaGlioblastoma MultiformeGlioma, MalignantGBMBrain CancerGlioblastoma, IDH-wildtypeGlioblastoma Multiforme, Adult

Part of Brain & nervous system, Cancer clinical trials.

This Phase 3 trial tests whether delivering a cancer drug directly into brain blood vessels, along with standard radiation and temozolomide, works better than standard treatment alone in newly diagnosed glioblastoma (GBM). The goal is to improve control of the tumor while comparing side effects between the two approaches.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
432 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are age 18 or older
  • You have a confirmed diagnosis of GBM with specific tumor features (not certain other brain tumor types)
  • You can do daily activities fairly well (Karnofsky score 70% or higher)
  • You have not started chemotherapy or radiation yet for your GBM diagnosis
  • You must be able to have MRI scans and enough recent blood-test and liver/kidney function results
  • Women who could become pregnant must have a negative pregnancy test and use reliable birth control

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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