Testing how mild heat affects depression symptoms and brain signals
Part of Injuries & trauma, Mental health clinical trials.
This study tests whether controlled whole-body heat can change immune-related brain and body signals in people with major depressive disorder. It may help researchers understand why heat affects mood and who might benefit, while closely monitoring safety.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18–65 years old and can speak English
- You have a current diagnosis of major depressive disorder for at least 4 weeks
- Your depression symptoms are high enough (clinician-rated score of 24 or higher)
- You can sign informed consent and follow study safety rules
- If you could become pregnant, you must use reliable birth control during the study
- You do not have certain other mental health conditions or recent severe risk factors
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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