Clinical trials
Hyperthermia clinical trials
Below are recruiting hyperthermia clinical trials, each written for real people, not researchers. We’re tracking 34 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06384053Recruiting
Heat plus radiation for skin cancer in older adults
This trial tests whether adding heat therapy (hyperthermia) to radiation therapy works well for older adults with larger non-melanoma skin cancers. It may help shrink tumors without needing surgery.
Aarau, Canton of AargauAges 65 years+ - NCT03249519Recruiting
Radiation plus heat for advanced cervical cancer
This trial studies whether adding controlled heat (“hyperthermia”) to radiation therapy (or radiation with chemotherapy) can improve outcomes in advanced cervical cancer. It focuses on people who can safely receive intensive pelvic radiation and heat treatment.
ErlangenAges 18 years+ - NCT03238378Recruiting
Radiation boost plus warming for recurrent head and neck tumors
This trial tests a “salvage” treatment that combines targeted radiation (brachytherapy) with controlled body warming (hyperthermia) for head and neck cancer that has come back. It may help by better shrinking tumors while fitting the treatment to the tumor’s exact location.
ErlangenAges 18 years+ - NCT05402839Recruiting
Screening people who may be prone to malignant hyperthermia
This study looks at people who had a dangerous anesthesia reaction called malignant hyperthermia during or after surgery. It may help teams figure out who might be at risk in the future so they can take safer steps next time.
Beijing, Beijing MunicipalityAges birth–100 years - NCT05366270Recruiting
Testing how mild heat affects depression symptoms and brain signals
This study tests whether controlled whole-body heat can change immune-related brain and body signals in people with major depressive disorder. It may help researchers understand why heat affects mood and who might benefit, while closely monitoring safety.
Boston, MassachusettsAges 18–65 - NCT05821166RecruitingPhase 2
Whole-body heat therapy to boost cancer treatment response
This study tests whether controlled whole-body heat, given along with standard cancer treatment, can help those therapies work better. It is designed for several specific advanced cancers in situations where care is focused on symptoms and tumor control.
BerlinAges 18–100 - NCT05993910Recruiting
Hyperthermia treatment database for cancer patients
This study collects information from cancer patients receiving hyperthermia treatment, which uses heat to help fight cancer. It helps doctors learn more about how well hyperthermia works and how safe it is.
BerlinAges Any age - NCT05397262Recruiting
Bladder cancer treatment with radiation plus heat therapy
This trial studies adding “heat treatment” (hyperthermia) to standard bladder cancer care using radiation, sometimes with chemotherapy. It may help the radiation work better, but your eligibility depends on cancer stage, your general health, and certain heart and metal-safety issues.
ErlangenAges 18 years+ - NCT07565350Recruiting
Heat and hydrogen peroxide for stubborn viral warts
This trial tests combining local heat therapy with a hydrogen peroxide solution to treat viral warts that haven't responded to other treatments like freezing or lasers. The goal is to find a new option for people frustrated by warts that keep coming back.
Shenyang, LiaoningAges Any age - NCT07564440Enrolling by invitation
Safety Study of Controlled Whole-Body Heat Treatment
This study tests whether a temperature management system can safely raise your body temperature to fever levels in a controlled medical setting. Researchers want to understand how your body responds and ensure the procedure is safe for future use.
Aventura, FloridaAges 18–65 - NCT07534865Recruiting
Heat and Hydrogen Peroxide Patch for Common Warts
This study tests a new patch that combines gentle heat with hydrogen peroxide to treat common warts on hands, feet, or fingers. The patch is applied directly to the wart and may help your body clear the infection.
ShenyangAges 6–65 - NCT07433036Recruiting
ER treatment study for overheating
This study tests how well emergency room protocols work for treating high body temperature. It is for healthy people who are not taking certain medications or supplements that affect how the body handles heat.
Colorado Springs, ColoradoAges 18–65 - NCT07372300RecruitingPhase 3
Heat therapy plus standard care for advanced rectal cancer
This trial tests whether adding modulated electro-hyperthermia (a gentle heat treatment) to standard therapy (radiation and chemotherapy) before surgery helps control locally advanced rectal cancer. It is for people whose cancer has not spread to other parts of the body.
Chiayi City, Dalin TownshipAges 20 years+ - NCT07235540Recruiting
Better temperature measurement during heat therapy for gynecological cancer
This trial tests a new device called a hyperthermia pelotte to measure vaginal temperature more accurately during heat therapy (hyperthermia) given alongside radiation for gynecological cancer. The goal is to improve the effectiveness and safety of treatment.
Rotterdam, South HolandAges 18 years+ - NCT07059819Enrolling by invitation
Local heat therapy for persistent high-risk HPV infection
This study tests whether local heat therapy can help clear a high-risk HPV infection that has lasted at least 3 months. It is for women who have no serious cervical cell changes or only mild changes (CIN) and who are generally healthy.
Shenyang, LiaoningAges 18–65 - NCT06835049RecruitingPhase 2
Heating therapy before surgery for high-risk soft tissue sarcoma
This trial tests a new approach for high-risk soft tissue sarcoma of the arm, leg, or trunk. Before surgery, you would receive chemotherapy combined with local hyperthermia (a treatment that gently heats the tumor area) to see if this can improve outcomes.
AarauAges 18 years+ - NCT06831981Recruiting
Heat therapy with chemo and radiation for rectal cancer
This trial tests if adding heat therapy (hyperthermia) to standard chemotherapy and radiation helps treat rectal cancer that has high-risk features. Heat therapy is thought to make cancer cells more sensitive to treatment.
Tübingen, Baden-WurttembergAges 18 years+ - NCT06812065Recruiting
Heat and hydrogen peroxide for skin warts
This trial tests whether applying heat combined with a common disinfectant (hydrogen peroxide) can safely and effectively remove viral skin warts. It may be an option if you have common, plantar, or genital warts and are between 16 and 65 years old.
Shenyang, LiaoningAges 16–65 - NCT06546969RecruitingPhase 1
Combination therapy for advanced bile duct cancer
This trial tests a combination of chemotherapy, immunotherapy, and heat therapy (hyperthermia) with a special radiation technique for advanced bile duct or gallbladder cancer that hasn't been treated before. It aims to see if this combination can help shrink tumors and improve outcomes.
Baltimore, MarylandAges 21 years+ - NCT06452485Recruiting
Re-irradiation with or without hyperthermia, or surgery only for recurrent breast cancer
This trial compares three treatment options for breast cancer that has come back in the chest or lymph nodes after previous radiation. It looks at adding hyperthermia (heating the tumor area) to re-irradiation, versus just re-irradiation or surgery alone, to see which offers better quality of life and survival with fewer side effects.
AmsterdamAges 18 years+ - NCT06249750RecruitingPhase 2
Heat shock therapy for castration-resistant prostate cancer
This trial tests a near-infrared whole-body heat shock technique to treat prostate cancer that no longer responds to hormone therapy. It aims to see if this heat-based approach can help control the cancer.
Hangzhou, ZhejiangAges 18–90 - NCT07793214Recruiting
Whole-body infrared hyperthermia for advanced solid tumors
This study looks at how well a treatment called whole-body infrared hyperthermia works for people with advanced solid tumors. The treatment uses heat to warm the whole body and may help fight cancer. The study will review medical records of people who already had this treatment at Zhejiang Hospital, and some people may join going forward.
Hangzhou, ZhejiangAges Any age - NCT07510061Recruiting
How your body handles mild heat
This study looks at how your body responds to mild heat depending on where you live and your specific traits. If you are a healthy adult in Denmark or Greece, you may be able to help researchers understand differences in heat resilience.
CopenhagenAges 18–65 - NCT07460180RecruitingPhase 1/Phase 2
PARP inhibitor with chemo and HIPEC for ovarian cancer
This trial tests if adding a drug called a PARP inhibitor (which helps block cancer cells from repairing themselves) to standard chemotherapy and heated chemotherapy during surgery (HIPEC) can work better together for ovarian cancer that has already been treated with initial chemo. It is for people with a specific type of advanced ovarian cancer who are planning surgery after chemo.
AmsterdamAges 18–100
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Hyperthermia trials by city
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Hyperthermia trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for hyperthermia?
- Yes. Clin2 currently lists 34 recruiting hyperthermia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hyperthermia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hyperthermia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.