Breathing medicine to help heart-lung machine separation after surgery
Part of Heart & circulation clinical trials.
This Phase 2 trial tests whether inhaled medicines (milrinone and epoprostenol) can make it easier to separate from the heart-lung machine during cardiac surgery. It may help reduce the risk of a difficult transition off the machine for the right patients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older and having cardiac surgery that uses a heart-lung machine (CPB).
- Your surgery should be aimed at a heart problem where correcting a congenital cardiomyopathy is not the main goal.
- You are not having a heart transplant or ventricular assist device surgery.
- Your surgery should not be urgent or you should not arrive in the operating room needing blood-pressure support medicines (vasopressors).
- Your team must be able to place an ultrasound probe through your esophagus (transesophageal ultrasound) and your neck spine must be stable.
- You must not have known reasons you cannot take milrinone or epoprostenol, such as certain valve/outflow blockage problems or an allergy.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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