Comparing two heart medicines during surgery
Treatments studied
Part of Heart & circulation clinical trials.
This study compares two medicines, milrinone and epinephrine, given during heart surgery to see which one helps the right side of the heart work better. It is for adults with some heart weakness before their operation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old.
- Your heart is pumping at least 40% of its normal ability (ejection fraction > 40%).
- The right side of your heart doesn't move as well as normal (TAPSE less than 1.7 cm).
- You do not have severe kidney or liver disease, uncontrolled high blood pressure in the lungs, or certain heart surgery risks.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 2 trial tests whether inhaled medicines (milrinone and epoprostenol) can make it easier to separate from the heart-lung machine during cardiac surgery. It may help reduce the risk of a difficult transition off the machine for the right patients.
This study compares two types of anaesthesia for people with a weakened heart (ejection fraction between 35-40%) who need planned lower-limb surgery. It looks at how each method affects blood pressure and heart function during and after the procedure.
This trial tests whether giving milrinone through a vein and inhaled during mitral valve surgery helps people with severe pulmonary hypertension. The goal is to improve heart and lung blood-flow stability around the time of surgery.
This early study looks at how well the heart is pumping in people with cardiogenic shock, using measurements taken during a right-heart catheter (a small pressure-monitoring test). It may help doctors better assess heart function and guide next-step treatments like LVAD, heart transplant, or valve surgery.
This trial studies whether an inotrope medicine (a drug that helps the heart pump) works better than a placebo in adults in intensive care with cardiogenic shock. It may help doctors find safer, more effective treatment for this life-threatening condition.
This trial tests if dexmedetomidine or methylprednisolone is better at reducing inflammation during coronary artery bypass grafting (CABG) with a heart-lung machine. The goal is to find a treatment that helps patients recover better.
Hear when a new Cardiac Anaesthesia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.