Clin2
NCT07144267Possibly a fitRecruiting

Comparing two heart medications during surgery

Cardiac AnaesthesiaCardiopulmonary Bypass

Treatments studied

Part of Heart & circulation clinical trials.

This trial compares two medicines, milrinone and epinephrine, given during heart surgery to see which one better helps the right side of the heart work. It may help patients with weaker right heart function.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
102 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You are between 18 and 70 years old
  • You are having heart surgery (not a repeat or re-exploration)
  • Your heart's pumping ability (ejection fraction) is above 40%
  • Your right heart function is reduced (TAPSE less than 1.7 cm)
  • You do not have severe lung problems (pulmonary hypertension) or kidney/liver disease

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06109155Recruiting· Phase 4
Comparing medications to reduce bleeding in heart surgery

This trial tests two medicines—ACT (a blood thinner) and tranexamic acid (a medicine to reduce bleeding)—to see which is better at controlling bleeding during heart surgery. It is for adults having planned heart surgery with a heart-lung machine.

Taichung
NCT04484675Recruiting· Phase 4
Milrinone during heart surgery for severe pulmonary hypertension

This trial tests whether giving milrinone through a vein and inhaled during mitral valve surgery helps people with severe pulmonary hypertension. The goal is to improve heart and lung blood-flow stability around the time of surgery.

Zagazig, Sharqia Province
NCT05450328Recruiting· Phase 2
Breathing medicine to help heart-lung machine separation after surgery

This Phase 2 trial tests whether inhaled medicines (milrinone and epoprostenol) can make it easier to separate from the heart-lung machine during cardiac surgery. It may help reduce the risk of a difficult transition off the machine for the right patients.

Montreal, Quebec
NCT07752303Enrolling by invitation
Comparing two anaesthesia methods for weak hearts

This study compares two types of anaesthesia for people with a weakened heart (ejection fraction between 35-40%) who need planned lower-limb surgery. It looks at how each method affects blood pressure and heart function during and after the procedure.

Sargodha
NCT07614438Not yet recruiting· Phase 2
Comparing blood pressure medications after pulmonary endarterectomy

This trial compares two medications, vasopressin and norepinephrine, to see which one better controls blood pressure in the lungs after surgery to remove blockages from the lung arteries. The goal is to find a treatment that keeps the lung blood pressure stable while minimizing side effects.

Le Plessis-Robinson
NCT05700617Recruiting· Early Phase 1
Testing cardiac pumping strength in cardiogenic shock

This early study looks at how well the heart is pumping in people with cardiogenic shock, using measurements taken during a right-heart catheter (a small pressure-monitoring test). It may help doctors better assess heart function and guide next-step treatments like LVAD, heart transplant, or valve surgery.

Chicago, Illinois

Hear when a new Cardiac Anaesthesia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.