Clin2
NCT05477589Possibly a fitRecruiting

Conditioning plan for kids with AML before stem cell transplant

Acute Myeloid Leukemia (AML) in RemissionStem Cell Transplantation

Part of Blood & lymphatic, Cancer clinical trials.

This Phase 3 trial studies the best “conditioning” chemotherapy plan before an allogeneic stem cell transplant for children with AML. It may help improve outcomes by testing an approach for kids who are ready for transplant after relapse or specific high-risk features.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
170 people
Ages
Up to 18 years
Study type
Interventional

Who can take part

  • You must be age 18 or younger when AML was first diagnosed (and 21 or younger at transplant).
  • You must have acute myeloid leukemia (AML) and your doctors must recommend a stem cell transplant with donated cells (not your own cells).
  • The transplant must be done at a hospital that is participating in this study.
  • You must not have certain other diseases (like MDS or JMML) instead of AML.
  • You must be healthy enough for chemotherapy (a poor activity score and major organ problems can disqualify you).
  • You must agree to the study and (if you can become pregnant) use reliable birth control and have a negative pregnancy test before treatment.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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