Clinical trial of radiation and chemotherapy before stem cell transplant for hard-to-treat AML
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests a combination of total body irradiation and two chemotherapy drugs (busulfan and melphalan) given before a stem cell transplant. It is for people with acute myeloid leukemia that has come back or not responded to standard treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 14 and 70 years old.
- You have AML that has relapsed (come back) or is refractory (didn't respond to treatment).
- You have a suitable donor for the stem cell transplant.
- Your heart, liver, and kidneys are working well enough, based on blood tests and heart tests.
- You are generally in good enough health to undergo the procedure (able to care for yourself and life expectancy at least 3 months).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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