Clin2
NCT05517980Possibly a fitNot yet recruiting

Drug KP104 for IgA or C3 kidney disease

Glomerulonephritis

Part of Immune system & allergy, Kidney & urinary, Women’s health & pregnancy clinical trials.

This Phase 2 study tests KP104 in people with IgA nephropathy (IgAN) or C3 glomerulopathy (C3G) to see if it improves kidney disease and is safe. It also tracks how the body handles the drug and how it affects disease markers in urine and blood.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
52 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • Be older than the study’s minimum age (not listed here) and weigh more than 35 kg
  • Have a BMI under 35
  • Have urine protein levels high enough: UPCR above 1.0 from a 24-hour urine test
  • Have a kidney biopsy-confirmed diagnosis of IgAN or C3G within the last 3 years
  • Be on a stable treatment plan for at least 6–12 weeks before screening (ACE/ARB and/or SGLT2, if applicable)
  • Agree to birth control rules if you can become pregnant, and have a negative pregnancy test if required

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04662723Recruiting· Phase 4
Personalized treatment for IgA kidney disease

This trial tests whether choosing treatment based on your personal kidney findings can improve outcomes in adults with IgA nephropathy (IgAN). It may help by matching therapy to the type and severity of kidney damage seen on biopsy.

Bari, BA
NCT07305974Recruiting· Phase 2
Study of RG002C0106 for primary IgA nephropathy

This phase 2a trial tests an experimental drug called RG002C0106 in people with primary IgA nephropathy. The goal is to see if the drug can reduce protein in the urine and protect kidney function.

Beijing, Beijing Municipality
NCT07445906Not yet recruiting· Phase 1
Exploring RG002C0106 in people with varying kidney function

This study tests a new medicine, RG002C0106, to see how it is processed in people with normal or mildly to moderately reduced kidney function. It helps researchers understand how kidney function affects the drug, which is important for future dosing recommendations.

NCT07390123Recruiting· Phase 3
Study of HSK39297 for IgA Nephropathy (IgAN)

This trial tests an experimental tablet, HSK39297, for people with IgA nephropathy, a kidney disease. It aims to see if the drug is safe and can help reduce protein in the urine, which is a sign of kidney damage.

Huangshan City, Anhui
NCT07616700Recruiting· Phase 2
Long-term safety study of HSK39297 for IgA kidney disease

This study continues treatment with an experimental medicine called HSK39297 for people with IgA nephropathy, a condition where the immune system damages the kidneys. The trial will track how safe and effective the medicine is over time in people who already completed an earlier study.

Beijing
NCT07474636Not yet recruiting· Phase 2
Study of HS-10542 for IgA nephropathy

This trial tests a new treatment called HS-10542 for people with IgA nephropathy, a kidney disease. It aims to see if the drug can safely reduce protein in the urine and help protect kidney function.

Beijing, Beijing Municipality

Hear when a new Glomerulonephritis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.