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NCT07553494Possibly a fitNot yet recruiting

SLN12140 treatment for IgA nephropathy in China

IgA Nephropathy (IgAN)

Treatments studied

Part of Immune system & allergy, Kidney & urinary, Women’s health & pregnancy clinical trials.

This trial tests a new medicine called SLN12140 for adults with IgA nephropathy, a kidney disease where the immune system damages the kidneys. The study aims to see if this medicine can slow kidney damage and reduce protein loss in urine.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
48 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You must be 18–80 years old and weigh at least 50 kg (males) or 45 kg (females)
  • You have IgA nephropathy confirmed by a kidney biopsy within the past 3 years
  • Your kidney function (eGFR) is at least 30 mL/min/1.73 m²
  • You have significant protein in your urine (at least 1.0 g/g during screening)
  • You have already been on standard kidney-protective medications (ACE inhibitors, ARBs, or SGLT2 inhibitors) for at least 12 weeks at a stable dose
  • You are willing to receive meningococcal and pneumococcal vaccines at least 14 days before starting the study medicine

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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