Clin2
NCT05528796Possibly a fitEnrolling by invitation

Finding causes of non-immune fluid buildup in babies

Non-Immune Hydrops Fetalis

Part of Blood & lymphatic, Genetic & congenital, Immune system & allergy, Women’s health & pregnancy clinical trials.

This study looks for the underlying cause of “non-immune hydrops fetalis,” a serious condition where a baby has abnormal fluid buildup. It focuses on families whose usual genetic tests didn’t find an answer (or weren’t completed before birth).

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
500 people
Ages
18 years to 60 years
Study type
Interventional

Who can take part

  • You are pregnant with a fetus diagnosed with non-immune hydrops fetalis and standard genetic tests were non-diagnostic
  • OR your baby was diagnosed before birth, but genetic testing couldn’t be finished or was delayed until after delivery
  • You are a biological parent of the fetus or baby with non-immune hydrops fetalis
  • The fluid buildup is not from twin-to-twin transfusion syndrome
  • The fluid buildup is not clearly caused by a viral infection
  • The fluid buildup is not due to blood-type mixing problems (alloimmunization)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06054230Enrolling by invitation
Genetic sequencing for fetal structural problems

This study offers genetic sequencing to find the cause of certain serious fetal problems, such as structural anomalies, severe growth restriction, or unexplained pregnancy loss after 14 weeks. It aims to help families understand why the issue occurred and guide future care.

San Francisco, California
NCT07194070Recruiting
Registry study for hemolytic disease in pregnancy

This study tracks pregnancies affected by hemolytic disease of the fetus and newborn (HDFN). It collects information to better understand the condition and improve care. You may join if you are pregnant with a history of a prior affected pregnancy and have a current antibody that could harm your baby.

Indianapolis, Indiana
NCT07790536Not yet recruiting
Genetic testing of fetal fluid for rare diseases after ultrasound concerns

This study uses advanced genetic testing on the fluid around the baby to look for rare diseases when an ultrasound shows possible problems. It aims to give more complete information to help you and your doctor make decisions during pregnancy.

Paris, Île-de-France Region
NCT06705543Recruiting
Genetic study of complex heart defects in unborn babies

This study looks at the genetic material in the fluid around the baby (amniotic fluid) and in the placenta to better understand complex heart defects in unborn babies. The goal is to find new clues that could help doctors care for these babies before and after birth.

Bordeaux
NCT07606989Recruiting
Genetic testing to understand fetal birth defects

This study uses advanced genetic testing (whole genome sequencing) on tissue samples from fetuses with structural abnormalities detected on ultrasound. The goal is to identify genetic causes of birth defects to help with diagnosis and understanding of your baby's condition.

Hangzhou, Zhejiang
NCT07515976Not yet recruiting
Genetic study for birth defects with unknown causes

This study looks for rare genetic changes that might explain birth defects when standard tests have not found a cause. It could help families understand why a baby has a structural problem and may guide future care.

Hear when a new Non-Immune Hydrops Fetalis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.