Clin2
NCT05540275Possibly a fitNot yet recruiting

Immunotherapy plus low-dose Avastin for return glioblastoma

Recurrent Glioblastoma

Treatments studied

Part of Cancer clinical trials.

This Phase 2 study tests tislelizumab (an anti–PD-1 immune therapy) combined with low-dose bevacizumab (Avastin) for recurrent glioblastoma that has already been treated with bevacizumab. If you qualify, you may be offered a new combination approach aimed at slowing tumor growth.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
30 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have a confirmed diagnosis of glioma (brain tumor) from pathology testing
  • You had brain tumor surgery at the study center, and a small reservoir was placed for a special fluid collection after surgery
  • You’re at least 28 days past surgery and have fully recovered with no major ongoing safety problems
  • Your daily function score is 70 or higher, and you’re expected to live more than 12 weeks
  • You have had no more than two prior recurrences of glioblastoma
  • You have not used key treatments that would disqualify you (see questions about prior Avastin, immune drugs, and radiation)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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