Pre-op vs post-op focused radiation for large brain metastases
Part of Brain & nervous system, Cancer clinical trials.
This study compares giving focused, high-dose radiation before surgery versus after surgery for people with large brain metastases. The goal is to see which timing works best to control the tumors and help neurological outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are over 18 years old
- You have confirmation of a solid cancer and at least one brain metastasis that needs surgery
- You can get focused MRI scans (MRI is not a problem for you)
- Your daily function is fairly good (KPS 70 or higher)
- You have 1 to 4 brain metastases, and one is large (over 2.1 cm across)
- Your cancer outside the brain is controlled or responding to treatment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares two ways of giving focused radiation for brain metastases: before surgery or after surgery. It aims to see which timing works better to control tumors while keeping you safe.
This trial compares giving stereotactic radiosurgery (focused radiation) before versus after surgery to remove brain metastases. It aims to see which timing may help control the cancer while possibly reducing side effects on thinking and memory.
This study looks at people with a small number of brain metastases who are treated with a focused, staged form of radiation after surgery or to treat the cancer. It may help doctors better understand how well this approach works and who benefits most.
This study compares giving focused, high-precision radiation before or after surgery for brain metastases. It aims to see which timing works best to control tumors and improve outcomes.
This trial tests giving powerful, precise radiation (stereotactic radiosurgery) to large brain tumors before surgery, then using more radiation after surgery. It aims to see if this approach can control the tumor better while reducing side effects.
This trial tests a new approach for people with a single large brain tumor that has spread from another cancer. You would receive a short, focused dose of radiation (stereotactic radiosurgery) in small, separate treatments, followed by surgery to remove the tumor. The goal is to see if this combination works better than the usual treatment.
Hear when a new Brain Metastases, Adult trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.