Clin2
NCT07329634Possibly a fitNot yet recruiting

Radiation before surgery for large brain tumors

Brain Metastasis

Part of Brain & nervous system, Cancer clinical trials.

This trial tests giving powerful, precise radiation (stereotactic radiosurgery) to large brain tumors before surgery, then using more radiation after surgery. It aims to see if this approach can control the tumor better while reducing side effects.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
98 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have at least one brain tumor (metastasis) that is between 2.5 and 6 centimeters in size and could be removed with surgery.
  • You have not had previous surgery on a brain metastasis, and you have not had whole brain radiation before.
  • You must be able to lie flat in a special head mask for the radiation treatment.
  • You have a diagnosis of cancer that started outside the brain (like lung, breast, or melanoma).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05102747Recruiting
Surgery-like brain radiation for up to 5 metastases

This trial compares two ways of giving focused radiation to the brain for people with a limited number of brain metastases. It aims to see which schedule works best (and is likely best for costs and quality of life).

Bordeaux
NCT06992973Recruiting
Radiation before surgery for large brain metastases

This trial tests a new approach for people with a single large brain tumor that has spread from another cancer. You would receive a short, focused dose of radiation (stereotactic radiosurgery) in small, separate treatments, followed by surgery to remove the tumor. The goal is to see if this combination works better than the usual treatment.

Rome
NCT06933199Recruiting
Focused radiation before brain tumor surgery

This study tests giving a single, precise dose of radiation to a brain metastasis just before surgery, to see if it helps control the tumor better without extra side effects. It’s for people who are already planning surgery for a medium-to-large brain tumor that started from another cancer.

Ostrava, Moravian-Silesian Region
NCT07227610Recruiting· Phase 2
Radiation for larger brain tumors that have spread

This study tests a type of radiation treatment for people with one or more brain tumors that are larger than usual (2 to 5 centimeters). It aims to see if this approach is safe and effective, and may be an option if you are not having immediate surgery.

Charleston, South Carolina
NCT07802353Recruiting
Focused radiation after brain tumor surgery

This study tests a type of radiation called stereotactic radiosurgery (SRS) given right after surgery to remove a brain tumor. The goal is to see if it helps control the tumor with fewer side effects.

Basking Ridge, New Jersey
NCT03750227Recruiting· Phase 3
Radiation before or after brain tumor surgery

This study compares giving focused, high-precision radiation before or after surgery for brain metastases. It aims to see which timing works best to control tumors and improve outcomes.

Scottsdale, Arizona

Hear when a new Brain Metastasis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.