Vagus nerve stimulation for Alzheimer's disease
Part of Brain & nervous system, Mental health clinical trials.
This trial tests a device that sends gentle electrical pulses to a nerve in the neck, which may help improve memory and thinking in people with mild to moderate Alzheimer's disease. It is for patients who have had a positive amyloid PET scan and are currently taking a stable dose of a cholinesterase inhibitor medication.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 50 and 85 years old.
- You have been diagnosed with mild to moderate Alzheimer's disease, confirmed by a positive amyloid PET scan.
- Your cognitive test scores are in a specific range (MMSE 16-24, CDR 0.5-2).
- You have been on the same dose of a cholinesterase inhibitor (like donepezil, rivastigmine, or galantamine) for at least 8 weeks.
- You can speak and understand Mandarin Chinese well enough to complete cognitive tests.
- You are willing to sign a consent form and follow the study procedures.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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