Implanted vagus nerve stimulator for mild to moderate Alzheimer’s
Part of Brain & nervous system, Mental health clinical trials.
This study tests whether an implanted vagus nerve stimulator can improve brain function in people with mild to moderate Alzheimer’s disease. It aims to target specific brain signaling pathways, and it will be compared against standard care while you continue your usual Alzheimer’s medicines.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with Alzheimer’s (mild to moderate stage) and have a positive amyloid PET scan
- You are 50 to 85 years old
- Your thinking/memory test scores are in a specific range (MMSE 16–24 and CDR 0.5–2)
- You have stayed on the same Alzheimer’s “cholinesterase inhibitor” medicine dose for at least 8 weeks
- You can do testing in Mandarin and sign consent to join
- You must be able to safely have brain MRI scans (no MRI contraindications)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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