Study brain artery narrowing causes in adults with antiphospholipid syndrome
Treatments studied
Part of Immune system & allergy clinical trials.
This study looks at how often the brain’s arteries become narrowed in people with antiphospholipid syndrome (APS), and why it happens. It may help you and doctors better understand the cause and how to detect it early using a brain MRI scan.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are an adult age 18 or older with a confirmed diagnosis of antiphospholipid syndrome (APS)
- Your APS diagnosis matches specific blood-test rules (positive antiphospholipid antibodies on two tests at least 12 weeks apart)
- You also meet at least one APS “clinical” history category (blood clot in a vessel or certain pregnancy-related problems)
- You can understand the study and sign informed consent
- You do NOT already have certain known brain/nerve conditions (like prior stroke or cerebral vasculitis/lupus affecting the brain)
- You can safely have an MRI with contrast (no gadolinium allergy, severe MRI/claustrophobia issues, incompatible implants, or kidney function too low)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study enrolls people age 40 or older who have at least 50% narrowing in one brain or neck (carotid) artery. It collects clinical information to better understand this condition and how patients are doing over time.
This study follows people after a stroke to better understand how the brain’s artery narrowing changes over time. It uses special 3D scans to see how blood flow and artery structure evolve, which may help future stroke prevention and treatment.
This study looks at a new way to measure stroke risk in people with a specific type of brain artery narrowing (atherosclerosis) in the front part of the brain. You might participate if you have this condition and are willing to have imaging tests and take standard medicines.
This study uses three advanced imaging methods (MRI, OCT, and angiography) to look at fatty plaques inside brain arteries and determine which ones are more likely to cause problems. It may help guide treatment for people with severe narrowing of an artery in the brain.
This study uses a special MRI scan to get detailed images of plaque buildup in the arteries of your brain or neck. The goal is to better understand these plaques and help guide treatment for people with narrowed arteries.
This study looks at how two types of blood vessel problems in the brain affect each other over time. It may help researchers better understand what to watch for and potentially how to improve outcomes.
Hear when a new Antiphospholipid Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.