Comparing imaging methods for brain artery plaque
Part of Brain & nervous system, Heart & circulation clinical trials.
This study compares three different imaging methods (MRI, OCT, and a special X-ray called angiography) to see which one best identifies dangerous plaque in the brain's arteries. If you have a severely narrowed brain artery, the study aims to help doctors predict stroke risk and choose the most effective treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have a severely narrowed artery in your brain (about 70–99% blockage).
- You need to have a brain angiogram (a special X-ray of your brain's blood vessels) and an OCT (a tiny camera that looks inside the artery) within a week of the MRI.
- You must not have any metal implants or other reasons that make an MRI unsafe (like severe claustrophobia).
- Your kidneys must be working well (no serious kidney failure).
- You must not be allergic to iodine or the contrast dye used in the imaging tests.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study uses a special MRI technique to take detailed pictures of the walls of narrowed arteries in the brain or neck. It aims to better understand the plaques that cause the narrowing, which may help guide treatment. If you have moderate to severe narrowing in these arteries, this imaging could provide important information for your care.
This study investigates the build-up of fatty deposits called plaques in arteries of the brain and neck using two different strengths of MRI scanners. It aims to understand how well these MRI techniques can image the plaques, which could help doctors better diagnose and manage stroke risk.
This study looks at a new way to measure stroke risk in people with a specific type of brain artery narrowing (atherosclerosis) in the front part of the brain. You might participate if you have this condition and are willing to have imaging tests and take standard medicines.
This trial uses special brain MRI to look closely at plaque in certain brain arteries after an ischemic stroke (when a blood vessel is blocked). It may help researchers better understand which plaques are most dangerous soon after stroke.
This trial uses a detailed eye/brain imaging test (optical coherence tomography) to study people with significantly narrowed brain arteries after certain stroke-like events. It may help researchers better understand and monitor this condition to improve care.
This study follows people after a stroke to better understand how the brain’s artery narrowing changes over time. It uses special 3D scans to see how blood flow and artery structure evolve, which may help future stroke prevention and treatment.
Hear when a new Intracranial Atherosclerotic Stenosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.