Nerve stimulation trial for children with steroid-resistant kidney syndrome
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This pilot study tests a device that stimulates nerves in the ear to help children with steroid-resistant nephrotic syndrome. It may improve urine protein and kidney-related outcomes for kids whose standard steroid treatment does not work.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Child is ages 3–17
- Nephrotic syndrome does not go into remission after 4 weeks of standard-dose prednisone
- Kidney function is enough for the study (eGFR 30 or higher)
- Kidney biopsy shows minimal change disease or focal segmental glomerulosclerosis
- Urine protein is still high (urine protein:creatinine ratio over 1.0)
- Uses stable anti-inflammatory medicines and an ACE inhibitor or ARB for at least 3 months
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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