Study of an injection for nephrotic syndrome in children
Treatments studied
Part of Immune system & allergy, Kidney & urinary clinical trials.
This study tests an injection (SG301) that targets a protein called CD38 to help children whose nephrotic syndrome keeps coming back or depends on steroids. The goal is to see if the treatment can reduce relapses and the need for steroids.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 6 and 18 years old.
- You have steroid-sensitive nephrotic syndrome that comes back often (frequent relapses) or depends on steroids.
- Your kidney function is normal (eGFR 90 or higher).
- Your morning urine test shows little to no protein for at least 3 days in a row after steroid treatment.
- No use of certain immune-suppressing medications in the last 2 to 6 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new drug called telitacicept to help children whose nephrotic syndrome keeps coming back often or who need steroids to stay in remission. The goal is to see if it can keep urine protein levels low and reduce relapses.
This trial tests if a hormone called ACTH can help children with nephrotic syndrome who have frequent relapses or need steroids to stay in remission. It aims to find a treatment that may reduce the need for steroids and prevent relapses.
This study looks at children newly diagnosed with nephrotic syndrome to understand how genes and proteins in the blood might predict the disease's course and response to treatment. By collecting samples, researchers hope to find markers that could guide better, more personalized care for future patients.
This trial tests if dupilumab can help children with nephrotic syndrome who still have relapses despite standard treatments. It aims to find a better way to control the disease and reduce steroid side effects.
This pilot study tests a device that stimulates nerves in the ear to help children with steroid-resistant nephrotic syndrome. It may improve urine protein and kidney-related outcomes for kids whose standard steroid treatment does not work.
This trial tests whether a small non-surgical device can help keep children with steroid-sensitive nephrotic syndrome in remission. If it works, it could lower the chance of relapse (kidney flare-ups) and help maintain kidney health.
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