Kidney nerve ablation to treat hard-to-control blood pressure
Part of Heart & circulation clinical trials.
This trial tests a procedure that targets nerves near the kidney (renal denervation) to help lower blood pressure in people whose hypertension is not controlled despite medication. It uses a special 3D mapping system to guide the procedure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re between 18 and 70 years old, and you can’t be pregnant or planning pregnancy in the next year
- You have high blood pressure that is essential (not caused by another disease), and you either can’t tolerate medicines or they’re not controlling it
- Your 24-hour blood pressure is high (average top number at least 130, or daytime at least 135) and your pulse pressure difference is under 80
- In the last 6 months, you used blood pressure medicines, and before enrollment you took a standardized plan with at least two drugs for at least 28 days with at least 80% adherence
- Your kidneys are functioning enough (eGFR at least 45) and you’re okay to undergo the surgical kidney procedure
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a procedure called renal denervation, which uses energy to calm overactive kidney nerves that can raise blood pressure. It is for people with mild high blood pressure who have not taken blood pressure medication for at least four weeks.
This trial tests a new way to perform a procedure called renal denervation, which uses radio waves to calm overactive kidney nerves that can raise blood pressure. By getting feedback during the procedure, doctors hope to make the treatment more effective for people with high blood pressure.
This study tests a new device that uses energy to calm kidney nerves, which may help lower blood pressure in people with chronic kidney disease whose blood pressure stays high despite taking multiple medications.
This trial tests whether stimulating nerves around the kidney can lower blood pressure in people whose high blood pressure stays uncontrolled despite treatment. It may help by improving how the kidneys and blood vessels regulate blood pressure.
This trial tests a procedure called renal denervation to lower blood pressure in people whose medication isn't enough. It uses a special catheter to calm nerves near the kidneys that may be overactive.
This trial tests a procedure called renal denervation, which uses targeted energy to calm overactive kidney nerves that can raise blood pressure. It is for people with high diastolic blood pressure (the bottom number) who have not yet taken blood pressure medication.
Hear when a new High blood pressure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.