Half or full thyroid surgery for low-risk thyroid cancer
Part of Cancer, Hormones & metabolism clinical trials.
This study looks at people with low-risk thyroid cancer who have already had (or are about to have) surgery, comparing half-thyroid removal versus full-thyroid removal. It may help doctors choose the safest and most effective surgery for your cancer type and risk level.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 16 or older.
- You have (or had) a “low-risk” type of differentiated thyroid cancer (papillary or follicular/oncocytic/Hürthle cell).
- Your tumor size is 4 cm or smaller, and it appears limited to the thyroid (or only minimal spread outside the thyroid).
- Your lymph node involvement is either none or limited to 5 or fewer small cancer spots, with no spread outside the lymph node.
- You have no distant spread (no metastasis), and your final surgery margins are not “R2” (meaning no remaining visible tumor).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether it is safe to monitor small, low-risk thyroid cancers (1–4 cm) instead of removing the remaining thyroid tissue after initial surgery. It may help you avoid a second operation and lifelong medication if your cancer is truly low-risk.
This trial tests whether it is safe to avoid immediate surgery and instead monitor small thyroid cancers that are considered low-risk. If you join, doctors will check regularly to make sure the cancer does not grow or spread.
This study compares a less invasive procedure (microwave ablation) with traditional surgery for treating a small, low-risk papillary thyroid cancer. If you have a single, small tumor with certain low-risk gene changes, you might be able to avoid surgery and have a quicker recovery.
This trial is testing whether thyroid hormone replacement after surgery is safe for people with low-risk papillary thyroid cancer. It may help maintain normal hormone levels after part of the thyroid is removed.
This study compares two surgeries for thyroid cancer that is only in the isthmus (the middle part of the thyroid): one removes just the isthmus, the other removes the whole thyroid. It aims to see which is better for patients with low-risk cancer.
This study compares three approaches for people with small, low-risk thyroid cancer: surgery, heat ablation (a less invasive procedure that uses heat to destroy the tumor), or simply watching it over time. The goal is to see which approach is safest and best for quality of life.
Hear when a new Differentiated Thyroid Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.