Oral medicine to help children stay calm for MRI scans
Treatments studied
This early study (Phase 1) tests whether an oral medicine called dexmedetomidine can help children feel calmer and be safely sedated for a brain MRI. It may help make MRI scans easier for young children who need general anesthesia.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 3 to 6 years old (boy or girl), any race or ethnicity
- Need an MRI that your doctor already recommends, done with general anesthesia
- Be able to take the oral dexmedetomidine (and you agree to it)
- Do not have a known allergy to dexmedetomidine
- Be able to take it at least 90 minutes before the MRI starts
- Not have certain heart, breathing, or medication-related problems that make sedation unsafe
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study uses MRI to measure oxygen in the brains of children (birth to 7 years) who need anesthesia for a routine scan. It aims to learn more about brain blood flow in different conditions.
This study tests whether giving a calming medicine before general anesthesia improves how children feel and experience anesthesia afterward. The goal is to see which pre-surgery approach works best and is comfortable for kids.
This trial studies how a baby’s brain uses oxygen during an MRI, using specific anesthesia medicines. It may help researchers better understand how anesthesia affects brain oxygen measurements in very young children.
This trial tests a nasal spray sedative (dexmedetomidine) to help children stay calm during a brain MRI. It may be an option if your child struggles with the scan due to age or cooperation issues.
This trial tests whether using one sleep medicine (propofol) alone works as well as using it with another medicine (dexmedetomidine) for children getting an MRI. The goal is to find the safest and most effective way to help kids stay still during the scan.
This study tests a combination of two medicines (dexmedetomidine and esketamine) given as a nasal spray to help children relax before surgery. The goal is to find the best dose that works well with the least side effects.
Hear when a new Anesthesia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.