Y-90 radioembolization plus treatment for high-risk liver cancer
Part of Cancer, Digestive system clinical trials.
This Phase 2 trial tests TheraSphere® (a Y-90 radiation treatment delivered to the liver) combined with standard systemic therapy in people with high-risk hepatocellular carcinoma (HCC). It aims to shrink tumors and improve outcomes for people whose liver cancer is at higher risk to worsen.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have confirmed hepatocellular carcinoma (liver cancer), staged as Child-Pugh A or B7.
- You have at least one tumor spot that can be measured on scans (including a previously treated spot that has clearly grown).
- You can have had prior cancer treatments (including none), but you cannot have had prior PD-1/PD-L1 treatment for any cancer.
- You are age 18 or older, with a performance status (energy/function) score of 0–2.
- Your blood counts and organ tests must be strong enough for treatment (including certain hemoglobin, kidney, liver, and clotting levels).
- If you can become pregnant (or are a sexually active male with a partner who can), you must use two forms of birth control and have a negative pregnancy test before starting.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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