Brain stimulation surgery for OCD using a guided DBS system
Part of Mental health clinical trials.
This trial studies whether deep brain stimulation surgery—guided using special scans—can reduce severe obsessive-compulsive disorder (OCD) symptoms. It may help people whose OCD has not improved enough with standard medicines and therapy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 22 and 75 years old when you are screened
- Have OCD for more than 5 years with symptoms that take over 1 hour a day or cause major distress or impairment
- Have severe OCD symptoms right now, based on a clinician-scored checklist (Y-BOCS score 28 or higher)
- Have tried the usual OCD treatments and still had severe symptoms (at least two SSRI antidepressants, plus other add-on treatments, plus exposure and response prevention therapy)
- Be able to stay on your current mental health medications and avoid starting new exposure therapy (ERP) until the study says it’s safe
- Live within 6 hours of the study site and have reliable support (stable housing and at least two emergency contacts) for about 18–24 months
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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