Clin2
NCT05624996Possibly a fitRecruiting

Targeted high-dose radiation added to standard lung cancer treatment

Locally Advanced Lung Non-Small Cell CarcinomaStage IIB Lung Cancer AJCC v8Stage III Lung Cancer AJCC v8

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This trial tests whether adding high-dose, targeted radiation to the usual treatment helps people with locally advanced, non-operable lung cancer live longer or better control the cancer. It may help shrink tumors in the chest and improve outcomes when surgery can’t be done.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
474 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have non-small cell lung cancer that can’t be removed by surgery (stage IIB or III) and it has spread to lymph nodes
  • Your lung cancer diagnosis is confirmed by lab testing (biopsy/sputum/cytology), and your tumor size is 7 cm or smaller
  • Your scans show no spread to distant organs (no distant metastases) within 60 days of starting the study
  • You can have the needed pre-treatment tests, including brain MRI (preferred) or CT, and a CT chest with contrast
  • You are at least 18 years old, can do usual activities with some limits (ECOG 0–2), and your blood/organ tests are adequate for chemo and radiation
  • You cannot have had radiation to the same lung cancer area before, and you must have an identifiable primary tumor (not T3–4N0 or T0N1–3)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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