Low-dose heart-rate medicine after surgery in frail older adults
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether a low dose of esmolol (a short-acting heart-rate medicine) can reduce heart muscle injury after non-heart surgery in older, frail people. It may help lower the chance of heart-related complications around the time of surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 65 or older
- You are having non-cardiac surgery (surgery not focused on the heart)
- Your overall health risk score (mFI) is at least 0.21
- Your anesthesia health class (ASA) is I to IV
- You are able and willing to join the study
- You are expected to stay in the hospital at least 3 days
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a sedative called remimazolam can help protect the heart during surgery in older adults. If you are 65 or older and having a longer surgery with general anesthesia, this trial may be for you.
This trial tests if esmolol, a heart-slowing drug, can improve oxygen levels in patients with acute respiratory distress syndrome (ARDS) who are on a breathing machine. It may help by adjusting heart rate to a specific range.
This study tests if giving a fast-acting heart medication (esmolol) early through an IV can protect the heart muscle during a heart attack. It may help patients who cannot receive a standard treatment due to certain risks.
This trial studies whether special care planning before non-cardiac surgery can improve outcomes for older adults with signs of heart stress. If you are 65 or older and scheduled for a moderate- to high-risk surgery, you may be able to join.
This trial tests a short-acting medicine called landiolol to see if it can prevent dangerously fast heart rates during and after major surgery. It is for people who have heart risks and are having a planned non-cardiac surgery.
This trial tests a medication called esmolol (a short-acting beta-blocker) to see if it can improve blood flow in tiny blood vessels (microcirculation) and help stabilize blood pressure in people with septic shock who have a fast heart rate. The goal is to see if slowing the heart rate can improve organ function and recovery.
Hear when a new Frailty trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.