Esmolol for blood flow in septic shock
Treatments studied
Part of Infections clinical trials.
This study tests a medication called esmolol to see if it helps blood flow in tiny blood vessels under the tongue for people with septic shock. If you have a fast heart rate despite treatment, this trial may help your doctors better manage your condition.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 85 years old.
- You have septic shock and need a medication to keep your blood pressure up.
- Your heart rate is 95 beats per minute or higher, even after treatment.
- You have not taken a beta-blocker (heart rate medication) in the last 24 hours.
- You do not have severe heart disease, lung disease, or other conditions that would make the study drug unsafe.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether adding a sedative called dexmedetomidine, along with your current care, can improve blood flow in small blood vessels under the tongue for people with septic shock in the ICU.
This study tests whether a medicine called anisodamine can improve blood flow in tiny vessels (microcirculation) under your tongue and help stabilize blood pressure in patients with septic shock. It may offer a new way to support recovery in the ICU.
This study tests a heart-slowing medicine called esmolol (a beta-blocker) in people with septic shock and a fast heart rate. It uses ultrasound to see if the medicine is safe and helpful.
This Phase 3 trial tests whether landiolol (a short-acting heart-rate–lowering medicine) can improve blood circulation in adults with septic shock whose heart rate is too fast. Doctors will also check that the medication is safe in this critical-care setting.
This trial studies how blood flow and organ “perfusion” look in ICU patients who are struggling with infection and low blood pressure. It may help doctors better measure and manage shock by comparing hemodynamic readings during standard treatment.
This trial studies how norepinephrine affects the heart and circulation in adults with septic shock whose blood pressure stays low after the first day. It may help doctors better choose and adjust medicines to support blood pressure and organ function.
Hear when a new Septic Shock trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.