Testing growth hormone and liraglutide effects on hunger hormones
Treatments studied
Part of Bones, joints & muscles, Brain & nervous system, Hormones & metabolism clinical trials.
This study tests how growth hormone (GH) and liraglutide affect a hunger-related hormone system called AgRP. It compares effects in healthy people (lean or overweight) and in people with isolated GH deficiency, aiming to understand how these treatments change appetite and metabolism.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be age 18–45 and either healthy (lean or overweight) or have isolated GH deficiency
- For healthy volunteers: no medical conditions besides being overweight/obese, and no prescription drugs
- For healthy volunteers: blood pressure and diabetes screening tests must be in a normal range (no diabetes)
- For GH-deficient volunteers: isolated GH deficiency diagnosis from an official stimulation test within the last 12 months, and no GH treatment in the last 12 months
- If you can become pregnant: you must use nonhormonal birth control during the study
- No smoking, major recent weight change, pregnancy/breastfeeding, or very heavy exercise right around screening
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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