Clinical trials
Uncontrolled Hypertension clinical trials
Below are recruiting uncontrolled hypertension clinical trials, each written for real people, not researchers. We’re tracking 23 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07090161RecruitingPhase 2
Study of iloperidone for uncontrolled high blood pressure
This trial tests if iloperidone can lower blood pressure in people whose high blood pressure is not controlled by current medications. You may qualify if your blood pressure is still high after weeks of treatment.
Phoenix, ArizonaAges 18–65 - NCT07142356RecruitingPhase 2
Modified release RTN-001 for uncontrolled high blood pressure
This trial tests a new modified-release drug, RTN-001, to see if it can help people whose blood pressure remains high despite taking at least two standard blood pressure medicines. You will take either RTN-001 or a placebo, and researchers will monitor your blood pressure closely.
Tucson, ArizonaAges 18–70 - NCT07654140RecruitingPhase 2
Testing a new drug for uncontrolled high blood pressure
This trial tests a new drug called SAL0140 for people whose high blood pressure is not controlled by current treatments. It may help lower blood pressure when other medications haven't worked well enough.
Beijing, Beijing MunicipalityAges 18–75 - NCT06676553RecruitingPhase 4
Optimized kidney nerve treatment for high blood pressure
This trial tests a new way to perform a procedure called renal denervation, which uses radio waves to calm overactive kidney nerves that can raise blood pressure. By getting feedback during the procedure, doctors hope to make the treatment more effective for people with high blood pressure.
TaipeiAges 18 years+ - NCT06938633Recruiting
Blood pressure study using urine test
This study uses a urine test to see if patients with high blood pressure are taking their medications correctly. The goal is to help you and your doctor improve your blood pressure control.
SingaporeAges 21–80 - NCT06527794Recruiting
Remote blood pressure management for Black patients
This study tests a remote program to help Black patients manage high blood pressure from home. You would use a blood pressure monitor and have phone or video visits with your care team.
Winston-Salem, North CarolinaAges 21–85 - NCT05732727RecruitingPhase 3
Stronger BP lowering using diuretics in kidney disease
This Phase 3 trial compares a plan that uses diuretics (water pills) to lower blood pressure more, versus usual blood pressure care, in people with uncontrolled hypertension and moderate-to-severe chronic kidney disease. It may help your blood pressure control while monitoring safety closely because kidney function changes how medicines work.
AngersAges 18 years+ - NCT06610448Recruiting
Wearable blood pressure monitoring study for Boston adults
This study tests a wearable device that tracks your blood pressure throughout the day while you go about your normal routine. If you live in the Boston area and are willing to wear the device, you may help improve how blood pressure is measured outside the doctor's office.
Boston, MassachusettsAges 18–100 - NCT05234788Recruiting
Radial-access kidney nerve procedure for hard-to-control high blood pressure
This trial tests a procedure that uses a catheter through the wrist or thigh to quiet overactive nerves in the kidney artery. It aims to lower blood pressure in people whose high blood pressure stays uncontrolled despite using multiple blood pressure medicines.
BordeauxAges 18–75 - NCT05934383Recruiting
Ultrasound treatment to lower blood pressure after kidney transplant
This trial tests whether ultrasound “renal denervation” can safely and effectively lower blood pressure in people whose hypertension is not well controlled after a kidney transplant. If you qualify, the study may help you see whether this procedure reduces office and 24-hour blood pressure readings without harming your transplanted kidney.
RotterdamAges 18 years+ - NCT07115953Recruiting
Spiral nerve treatment for uncontrolled high blood pressure
This trial tests a new procedure to treat high blood pressure by using a special catheter to calm overactive nerves in your kidneys. It may help you achieve better blood pressure control if medications are not enough.
MelbourneAges 18 years+ - NCT07465549Recruiting
A smarter way to manage hard-to-control high blood pressure
This trial uses a special blood pressure monitor (CART BP Pro) to help guide treatment for people whose blood pressure stays high despite standard care. You may qualify if your blood pressure is still too high even with medication.
AnsanAges 19 years+ - NCT07489612Enrolling by invitationPhase 2
Testing QLS1410 for people with hard-to-control high blood pressure
This trial is testing an experimental drug, QLS1410, to see if it can lower blood pressure in people whose blood pressure is still high even after taking two or more medications.
JinanAges 18 years+ - NCT03206814Recruiting
Mobile app coaching to improve high blood pressure control
This trial tests whether a smartphone app with remote care (telecare) can help people with hard-to-control high blood pressure reach better blood pressure numbers. It may help you and your care team monitor progress more closely at home.
Bahía BlancaAges 18–80 - NCT07005050Recruiting
Kidney nerve treatment for high blood pressure pilot study
This study tests a new treatment that uses a device to calm overactive nerves in the kidneys, which may help lower high blood pressure. It is for people who are already taking at least two blood pressure medications and still have high readings.
Birmingham, AlabamaAges 21–80 - NCT07450222Enrolling by invitation
Improving high blood pressure care
This trial studies a new way to help people with high blood pressure get better control of their numbers. It uses a team approach to support you in managing your blood pressure and lowering your risk for heart problems.
Peoria, IllinoisAges 18 years+ - NCT05421767RecruitingPhase 4
Renal nerve stimulation for hard-to-control high blood pressure
This trial tests whether stimulating nerves around the kidney can lower blood pressure in people whose high blood pressure stays uncontrolled despite treatment. It may help by improving how the kidneys and blood vessels regulate blood pressure.
TaipeiAges 20 years+ - NCT07130955Enrolling by invitation
Ablation for hard-to-control high blood pressure with kidney disease
This study tests a new device that uses energy to calm kidney nerves, which may help lower blood pressure in people with chronic kidney disease whose blood pressure stays high despite taking multiple medications.
Beijing, Beijing MunicipalityAges 18–65 - NCT02804074Recruiting
Treat “hidden” high blood pressure using 24-hour monitoring
This study looks at better treatment for people whose blood pressure looks okay in the clinic, but stays high during daily life or at night. It uses 24-hour blood pressure monitoring (a test that checks readings throughout the day) to guide care and see if it helps control “masked uncontrolled” hypertension.
MilanAges 35–80 - NCT07051603RecruitingPhase 1
Safety study of SAL0140 in healthy Chinese adults
This study tests the safety and how the body handles a new medicine (SAL0140) in healthy people. It helps doctors find the right dose and check for side effects.
Guangzhou, GuangdongAges 18–65 - NCT06543394Enrolling by invitation
Helping patients take blood pressure medication regularly
This trial tests whether a behavioral science approach can help people with high blood pressure take their medication as prescribed. If you have trouble remembering or sticking with your blood pressure pills, this study may help you find better ways to stay on track.
New York, New YorkAges 18 years+ - NCT07031739Recruiting
Managing high blood pressure and food insecurity
This study tests different ways to help people with high blood pressure who also struggle to get enough food. It aims to improve blood pressure control and reduce food insecurity.
Winston-Salem, North CarolinaAges 18 years+ - NCT06845579Recruiting
Predicting blood pressure results after kidney nerve treatment
This study tests a treatment called renal denervation, which uses a special procedure to calm nerves near the kidneys that can raise blood pressure. It may help people whose high blood pressure is not well controlled despite taking several medications.
Mainz, Rheinland PflanzAges 18 years+
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Uncontrolled Hypertension trials by city
Studies with a site in or near these metro areas.
Uncontrolled Hypertension trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for uncontrolled hypertension?
- Yes. Clin2 currently lists 23 recruiting uncontrolled hypertension studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a uncontrolled hypertension trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a uncontrolled hypertension trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.