Tumor-pulse device for spinal cancer fluid spread
Part of Brain & nervous system, Cancer, Lungs & breathing, Skin clinical trials.
This trial tests whether Tumor Treating Fields (a non-surgical device that delivers treatment signals to cancer cells through the scalp/skin) can help people whose breast or lung cancer has spread into the fluid around the spine and brain. It focuses on people who have cancer cells found in spinal fluid and can safely use the device most of the day.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older
- You have had breast cancer or lung cancer confirmed by a tissue biopsy
- Tests show cancer in spinal fluid (cerebrospinal fluid) plus MRI shows irritation/enhancement along the spine’s lining
- You can likely live at least 6 weeks and are well enough to do daily activities (ECOG 0–3)
- Your blood counts and organ function are high enough for treatment (for example, platelets > 25 and neutrophils above a minimum; kidney and liver tests meet limits)
- You must be able to place and wear the device on your skin for at least 18 hours each day
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a precise type of radiation to the brain and spine (craniospinal irradiation) can help control cancer that has spread to the lining of the brain and spinal cord (leptomeningeal disease) in people with breast cancer or non-small cell lung cancer. The goal is to improve symptoms and slow disease progression.
This trial compares a newer type of radiation (proton therapy) to standard radiation for people whose breast or lung cancer has spread to the lining of the brain and spinal cord. It aims to see if proton therapy can better control the disease while causing fewer side effects.
This trial tests a special type of radiation that avoids the memory center of the brain (the hippocampus) while treating cancer that has spread to the lining of the brain and spinal cord. It may help reduce side effects on thinking and memory for people with breast or lung cancer.
This trial tests a wearable device that puts low-intensity electric fields on the skin over spinal tumors to slow their growth. It's for people whose spinal metastases have already been treated with surgery and/or radiation and have no more radiation options.
This trial tests a new drug called BioTTT001 for people with non-small cell lung cancer (NSCLC) that has spread to the fluid around the brain or the lining of the brain (leptomeninges). The goal is to see if the drug is safe and can help control the cancer.
This study collects spinal fluid samples from people with advanced (metastatic) HER2-positive or triple-negative breast cancer who have never had, and currently do not have, cancer spread to the brain. Researchers want to understand how cancer cells might reach the nervous system and develop better treatments.
Hear when a new Anatomic Stage IV Breast Cancer AJCC v8 trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.