Test PD-1 drug plus azacitidine and donor cells for AML relapse
Treatments studied
Part of Blood & lymphatic, Cancer clinical trials.
This study tests whether combining a PD-1 immune therapy, azacitidine, and low-dose donor lymphocyte infusion (donor immune cells) can treat AML that has come back after a stem cell transplant. It may help some people regain anti-cancer immune activity after relapse.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have AML that has relapsed after a prior allogeneic stem cell transplant
- Your organs (kidneys, liver, etc.) are healthy enough for treatment
- You can understand the study and sign the consent form
- You are between 18 and 60 years old
- Your day-to-day functioning is good (ECOG 0–1)
- You have a matched donor who is able to provide donor cells (and you’re expected to live more than 3 months)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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