Early cholesterol-lowering to help reverse artery plaque
Part of Heart & circulation clinical trials.
This trial studies whether starting strong cholesterol-lowering treatment early can reduce or reverse plaque in the arteries. It may help protect the heart over time, especially for people with inherited high cholesterol.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with familial hypercholesterolemia (inherited high cholesterol) in one gene copy (heterozygous)
- You are an adult age 18 to 50
- Your LDL (“bad cholesterol”) is higher than 100 mg/dL (over 2.6 mmol/L) at the start of the study
- Your kidney function is not severely reduced (eGFR is 30 or higher)
- You have not had past heart or blood-vessel events from plaque (like heart attack or stroke)
- You do not have atrial fibrillation, an irregular heart rhythm
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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