Test noninvasive checks of blood flow in limb-threatening ischemia
Part of Heart & circulation, Hormones & metabolism clinical trials.
This study uses painless, noninvasive tests to measure blood flow in people with chronic limb-threatening ischemia. It may help doctors better understand circulation problems and track blood flow without procedures.
Summary written for real people, not researchers, by Clin2.
Who can take part
- If you have chronic limb-threatening ischemia (CLTI), you must be over 50
- If you are in the age-control group, you must be over 50 and have no heart or blood vessel disease
- For the control/healthy groups, you must have a normal-ish ankle-brachial index (ABI) between 0.9 and 1.3
- If you are in the healthy group, you must be age 18 to 50 and have no heart or blood vessel disease
- You must be willing to participate (volunteer)
- You must be able to understand the study and give informed consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new way to open blocked arteries below the knee in people with severe leg wounds due to poor blood flow (chronic limb-threatening ischemia). The goal is to help wounds heal and save the leg from amputation.
This study uses a special “radiotracer” scan to look at how well blood flows through the arteries in the legs. It may help researchers better understand circulation problems from peripheral artery disease.
This study tests a new device called the Spur to open blocked arteries below the knee in people with severe leg pain or minor wounds. It is specifically for people who also have diabetes or are on dialysis.
This trial tests whether using a special ultrasound probe inside the artery (called intravascular ultrasound) helps guide treatment for people with severe leg artery blockages that cause pain, wounds, or gangrene. The goal is to see if it improves blood flow and saves the leg.
This study checks how well blood flows in the legs of people with and without chronic wounds or circulation problems. It may help doctors better understand and treat poor circulation.
This trial uses a Doppler ultrasound to measure blood flow speed in your leg arteries to see if it can better predict a severe form of peripheral artery disease called critical limb ischemia. You may qualify if you have known artery disease in your leg and are already scheduled for a toe blood pressure test.
Hear when a new Chronic Limb-Threatening Ischemia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.