Exercise program for transthyretin heart amyloidosis
Part of Brain & nervous system, Genetic & congenital, Hormones & metabolism clinical trials.
This trial studies whether a structured exercise training program is safe and helpful for people with transthyretin (ATTR) cardiac amyloidosis. It may help improve fitness and daily functioning, and it may also compare groups for specific eligibility needs.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with ATTR heart amyloidosis (either by heart biopsy or a specific bone-scan blood flow test result).
- You have heart failure and your healthcare team has you using water pills (diuretics), plus a BNP blood test level at or above 450.
- You can walk about 4 meters (with or without a cane/walker) and manage basic daily activities on your own.
- At the time of starting the study, your heart condition is stable enough for study testing and exercise.
- You are not already doing regular moderate-to-vigorous exercise (more than 30 minutes per day, at least twice per week) for the past 6 weeks.
- You can follow the study plan and provide informed consent (and you don’t have major medical problems that block safe exercise).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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