Spironolactone for alcohol use disorder
Treatments studied
Part of Mental health clinical trials.
This Phase 1 study tests whether spironolactone (a medicine that affects salt and hormone balance) is safe and potentially helpful in people with alcohol use disorder. You may be eligible if you are currently drinking heavily, have low alcohol withdrawal symptoms, and meet several lab and medication safety rules.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be at least 21 years old
- Have alcohol use disorder, meaning you meet at least 2 criteria on an interview questionnaire
- In the last 28 days, have at least 4+ drinks on 4+ days if female, or 5+ drinks on 4+ days if male
- Have a recent alcohol withdrawal score (CIWA-Ar) under 10
- Have safe blood test results, including potassium not too high and kidney function not too low
- Agree to contraception rules: do not be pregnant, and follow the study’s birth control requirements
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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