Dexmedetomidine to prevent delirium after open-heart surgery
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This trial tests whether a sedating medicine called dexmedetomidine can reduce the risk of “delirium” (sudden confusion) in the intensive care unit after open-heart surgery. If you’re having certain heart operations, it may help protect your thinking and alertness during recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled for open-heart surgery that uses a heart-lung machine (cardiopulmonary bypass).
- You are having one of these surgeries: bypass (CABG), valve repair/replacement, or a combined surgery.
- Your heart pumping strength (left ventricular ejection fraction) is more than 40%.
- You do NOT have atrial fibrillation before surgery.
- You do NOT have certain slow heart rhythm problems (second/third-degree AV block, or resting heart rate ≤ 50).
- You do NOT have a pacemaker, major kidney/liver problems, or an emergency surgery plan.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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