Brain-modeling trial to predict depression treatment response
Treatments studied
Part of Mental health clinical trials.
This trial uses computer modeling based on brain measurements to try to predict which depression treatment will work for you. It may help match you with the most effective option faster by understanding your motivation-related brain patterns.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have major depressive disorder confirmed by DSM-5 criteria (not another mood diagnosis)
- Your depression severity is high (MADRS score 24 or higher)
- You need a new treatment for this current episode
- You have not already tried the usual antidepressant options for this episode recently (or you had a long enough wash-out)
- You can safely have an MRI scan (not pregnant/breastfeeding, not severely claustrophobic, and no metal implants that block MRI)
- You do not have treatment-resistant depression based on at least 2 adequate antidepressant trials that did not help
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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