Smart stent for severe leg artery blockages
Part of Heart & circulation clinical trials.
This trial studies a new “smart” stent placed in the thigh-to-knee artery to treat significant blockages. It may help improve blood flow to the foot, and you would be followed closely to see how well the stent works over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be over 18 years old
- Have a leg artery blockage that matches Rutherford score 2 to 5 (moderate to severe symptoms)
- Agree to return for follow-up visits at the scheduled times
- Have the stent target measured at least 150 mm long, with blockage worse than 50% or a blockage that is fully closed
- Have a guidewire successfully passed across the blockage before joining the study
- Expected to live at least 24 months
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a two-step treatment for long blockages in the leg artery: first, a device clears the plaque, then a drug-coated balloon is used to keep the artery open and prevent re-narrowing. It aims to improve blood flow and reduce symptoms like leg pain or wounds.
This study tests a new type of stent (called ZENFLEX Pro) to open blocked arteries in the leg. The stent helps improve blood flow and may reduce leg pain and help wounds heal, and may be a good option if your blockage is in the thigh or behind the knee.
This study is testing a new drug-coated stent for blocked arteries in the thigh or behind the knee. It may help people with moderate to severe leg pain or wounds by improving blood flow without needing surgery.
This study compares a new balloon-expandable stent to standard bare-metal stenting to treat complex blockages in the iliac arteries (main blood vessels to the legs). It may help people with symptoms like leg pain with walking, pain at rest, or minor tissue injury by improving blood flow and reducing repeat procedures.
This trial studies a drug-eluting dissolving scaffold placed in blocked arteries below the knee to improve blood flow. It may help people whose leg circulation problems are severe enough to limit walking or threaten the limb, but only if their blockages fit specific imaging and procedure requirements.
This trial tests a new minimally invasive procedure (placing a small stent) to improve blood flow to a severely threatened foot or lower leg. It may help people whose ulcers or gangrene are not treatable with standard bypass or other surgeries.
Hear when a new Peripheral Arterial Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.