Compare proton vs modern radiation effects on thinking
Part of Mental health clinical trials.
This study compares two types of radiation—proton therapy versus modern fractionated radiation—to see how they affect long-term thinking (cognitive function) and daily abilities in people with a specific skull-base tumor. It may help clarify which radiation approach best protects brain and nerve function over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a Grade 1 meningioma in/around the cavernous sinus area that is larger than 3 cm
- You’re an adult (over 18) and age 70 or under
- Your diagnosis is Grade 1 (confirmed by biopsy, or biopsy isn’t safe but scans/growth suggest Grade 1)
- You can do memory/thinking testing: your MoCA score meets the study’s cut-off, and you can follow study tasks
- Your general health/function is good: performance status 0 or 1
- You must be able to have MRI scans and sign consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares different radiation methods for treating a slow-growing, non-cancerous brain tumor at the base of the skull. It aims to see which approach best protects memory and thinking abilities.
This study looks at how radiation from brain tumor treatment affects memory, attention, and thinking skills in children. It uses brain scans and tests to understand these effects.
This study tests whether modern radiation methods—possibly including proton therapy—can treat intracranial meningioma while better protecting thinking and memory. It will look at imaging results and changes in neurocognitive (thinking/memory) function over time.
This study compares two types of radiation—protons and photons (X-rays)—for specific brain tumors or tumor returns. It aims to see which approach works best and is safest for you, based on how much and where the radiation is delivered.
This study compares two types of radiation therapy for adults with primary brain tumors that have a good outlook (expected survival longer than 5 years). You will receive either standard photon radiation or the more targeted proton radiation, to see if one works better or causes fewer side effects.
This trial compares two types of radiation therapy (proton beams vs. standard photon x-rays) for people with certain slow-growing brain tumors (gliomas) that have a specific gene change. The goal is to see which type better preserves thinking skills and quality of life while treating the tumor.
Hear when a new Proton Therapy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.