ECT plus a sleep monitor for treatment-resistant depression
Part of Mental health clinical trials.
This study looks at how electroconvulsive therapy (ECT) affects brain activity and sleep patterns in people with difficult-to-treat depression. It uses a wearable sleep monitor (the Dreem device) to record sleep while you receive ECT.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are being referred to start an initial ECT course for depression
- Your depression diagnosis includes treatment-resistant unipolar major depression or bipolar depression
- You have tried at least two antidepressant medicines at adequate dose and for long enough without full success
- You do not have schizophrenia or schizoaffective disorder
- You can tolerate wearing the Dreem device for sleep recordings
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies how brain activity relates to feelings and depression, using brain electrodes to measure signals. It’s meant for people with long-lasting, treatment-resistant major depression who may need stimulation while continuing psychiatric care.
This trial studies signs in the brain (biomarkers) during an accelerated form of nerve stimulation to treat depression that hasn’t improved with usual antidepressants. It may help researchers learn who benefits and how to better personalize treatment.
This trial studies better ways to deliver ECT (electroconvulsive therapy) for people with difficult-to-treat depression, including some people with bipolar depression. You may be offered an ECT strategy that’s tailored to your situation, with the goal of improving outcomes and reducing problems.
This study tests whether adding TMS to ECT can better treat depression that hasn't improved with other treatments. It is for adults with moderate to severe major depression who haven't had these treatments recently.
This study uses a comfortable headband to track your sleep and brain activity. It may help better understand when seizures are likely to happen.
This study measures changes in your blood and/or body chemistry while you receive electroconvulsive therapy (ECT) for a severe mood episode. The goal is to understand biological signals related to ECT and treatment-resistant depression, which may help improve future care.
Hear when a new Treatment Resistant Depression trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.