Optimizing ECT treatment for difficult depression
Part of Mental health clinical trials.
This trial studies better ways to deliver ECT (electroconvulsive therapy) for people with difficult-to-treat depression, including some people with bipolar depression. You may be offered an ECT strategy that’s tailored to your situation, with the goal of improving outcomes and reducing problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You (or your legally authorized representative) agree in writing after being told about the study.
- You are 18 years old or older.
- You have major depressive disorder or bipolar disorder with depression.
- You should be able to safely receive general anesthesia (no anesthesia contraindications).
- You must be able to speak Dutch for study discussions and assessments.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a way of adjusting (titrating) ECT treatment to improve outcomes in people with major depression or bipolar II. It’s mainly for those who already need ECT with right-side electrode placement.
This trial compares two anesthesia medicines—esketamine plus propofol versus methohexital—for people receiving ECT (electroconvulsive therapy) for severe depression. The goal is to see which anesthesia approach works better and is safer for patients during ECT.
This study tests whether a specific type of brain stimulation (theta burst delivered over several days) works better than standard rTMS given over 6 weeks for people with treatment-resistant depression. It may help improve depressive symptoms, measured with multiple depression rating scales.
This study looks for ways to predict how well electroconvulsive therapy (ECT) will work for severe depression. It may help doctors choose the best treatment approach and timing for future patients.
This trial studies which electrical “pulse settings” work best during electroconvulsive therapy (ECT) for people with depression. It may help doctors personalize ECT so the treatment is safer and works as well as possible for you.
This study measures changes in your blood and/or body chemistry while you receive electroconvulsive therapy (ECT) for a severe mood episode. The goal is to understand biological signals related to ECT and treatment-resistant depression, which may help improve future care.
Hear when a new Depression trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.