Clin2
NCT05911958Possibly a fitRecruiting

Study drug before surgery for HER2-low, HR-positive breast cancer

HER2 Low Breast Carcinoma

Treatments studied

Part of Cancer clinical trials.

This trial tests SHR-A1811 given before surgery (neoadjuvant treatment) for breast cancer that is hormone-receptor positive (HR-positive) and HER2-low. It aims to shrink or control the cancer early and see how well this approach works compared with standard care.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
66 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You are between 18 and 70 years old
  • You have not had any cancer treatment yet (no prior anti-cancer therapy or radiation, except some fully cured skin/cervix early cases)
  • Your breast cancer is HR-positive, HER2-low, and Ki-67 is over 14% based on lab testing
  • Your scans show no spread to distant organs (M0), and the cancer is not inflammatory
  • Your general health is good enough (ECOG 0–1) and your heart/lungs and blood/organ tests are acceptable

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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