Tadalafil to help breathing in COPD with pulmonary hypertension
Treatments studied
Part of Heart & circulation, Lungs & breathing clinical trials.
This Phase 2 study tests whether tadalafil can improve breathlessness in people with COPD and pulmonary hypertension (high blood pressure in the lungs). It may help you breathe more easily if your symptoms are driven by this specific lung circulation problem.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have COPD confirmed by breathing test results (FEV1/FVC below 70%) or emphysema on a chest CT scan
- You have pulmonary hypertension shown on recent tests (CT size, echo blood-pressure estimates, or a right-heart catheter test)
- You feel very short of breath, scoring at least 20 on a breathing-questions form
- You take at least one long-acting breathing medicine (a long-acting bronchodilator) for 4 weeks or more
- You’re between ages 35 and 89 (and you’re able to follow study visits and procedures)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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