Test a mouth device for sleep apnea after stopping CPAP
Part of Brain & nervous system, Lungs & breathing clinical trials.
This study looks at whether a mandibular advancement device (a fitted mouthpiece) can control sleep apnea when you temporarily stop CPAP. It’s mainly for people who have been using CPAP for over a year but are now willing to try the mouth device.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are willing to accept and try a mandibular advancement device (a custom mouthpiece)
- Your sleep study showed significant sleep apnea (AHI over 15 events per hour)
- You had notable daytime sleepiness during initial treatment (ESE over 10)
- You have been on CPAP for more than 12 months, using it on average more than 5 hours per night
- Your sleep apnea is not mainly “central” type (less than 5 central apneas per hour)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies how CPAP (a breathing machine) or a custom mouth guard (MAD) affects sleep over the long term in people with obstructive sleep apnea. It may help confirm which treatment improves sleep and how well it works over time.
This study compares two common treatments for moderate sleep apnea: a custom mouthpiece that gently advances your jaw, and a CPAP machine that blows air to keep your airway open. The goal is to see which treatment works better for improving sleep and daytime symptoms.
This study looks at a new way to use digital dental scans to fit a mouthpiece that treats obstructive sleep apnea. If you use this mouthpiece, the study may help make fitting more comfortable and accurate.
This study tests whether adding a special mouthpiece (mandibular advancement device) can help people whose sleep apnea wasn't fully treated by a nerve stimulator implant. You would use the mouthpiece at night and take home sleep tests to see if your breathing improves.
This study compares two types of dental mouthpieces used to treat sleep apnea. Participants will temporarily stop using their current mouthpiece for two weeks to see how they do without it.
This trial tests how well people accept a mouthpiece (mandibular advancement device) to treat obstructive sleep apnea (a condition where your breathing stops and starts during sleep). If you have sleep apnea and can wear a device that moves your lower jaw forward while you sleep, you may be able to join.
Hear when a new Endothelial Dysfunction trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.